by Dokterstatistik | Feb 3, 2021 | Theory
Wahyu Widhiarso | Fakultas Psikologi UGM
Banyak orang yang menghindari melakukan penelitian dengan menggunakan pendekatan Model
Persamaan Struktural (SEM) dengan alasan kompleksitas prosedur analisis SEM. Analisis dengan
menggunakan SEM memang sangat kompleks karena SEM merupakan analisis multivariat dengan banyak variabel. Namun dengan menggunakan AMOS, analisis SEM menjadi menarik dan menantang. AMOS menyediakan kanvas di dalam programnya agar peneliti menuangkan modelnya dalam bentuk gambar di dalam kanvas tersebut. Analisis menjadi semakin mudah karena dengan satu kali klik, gambar model yang dituangkan di dalam kanvas langsung dianalisis dengan lengakap. Makalah ini akan menyajikan prosedur analisis SEM melalui AMOS yang dilengkapi dengan beberapa informasi mengenai dasar-dasar SEM.
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by Dokterstatistik | Feb 3, 2021 | Theory
A B S T R A C T
Background: Data about the relationship between chest radiographs and sputum bacillary load, with
treatment outcomes, in patients with extensively drug-resistant tuberculosis (XDR-TB) from HIV/TB
endemic settings are limited. Methods: Available chest radiographs from 97 South African XDR-TB patients, at the time of diagnosis, were evaluated by two independent readers using a validated scoring system. Chest radiograph findings were correlated with baseline sputum bacillary load (smear-grade and culture time-to-positive in MGIT), and prospectively ascertained clinical outcomes (culture conversion and all-cause mortality). Results: Radiographic bilateral lung disease was present in 75/97 (77%). In the multivariate analysis only a higher total radiographic score (95% CI) was associated with higher likelihood of death [1.16 (1.05–1.28) p = 0.003], and failure to culture convert[0.85 (0.74–0.97) p = 0.02]. However, when restricting analyses to HIV-infected patients, disease extent, cavitation, and total radiographic scores were not associated with mortality or culture-conversion. Finally, cavitary, disease extent, and total radiographic scores all positively correlated with bacterial load (culture time-to-positive). Conclusions: In endemic settings, XDR-TB radiological disease extent scores are associated with adverse clinical outcomes, including mortality, in HIV uninfected persons. These data may have implications for clinical and programmatic decision-making and for evaluation of new regimens in clinical trials.
© 2018 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
